Educating patients on the benefits of fasting in the management of T2D

This case series documents three patients referred to the Intensive Dietary Management clinic in Toronto, Canada, for insulin-dependent type 2 diabetes. It demonstrates the effectiveness of therapeutic fasting to reverse their insulin resistance, resulting in cessation of insulin therapy while maintaining control of their blood sugars. In addition, these patients were also able to lose significant amounts of body weight, reduce their waist circumference and also reduce their glycatedhaemoglobin level.

This case study about three patients with type 2 diabetes illustrates that if patients are well informed about their condition with 6 hour lectures, as well as training in nutrition and the benefits of low carbohydrate diets and intermittent fasting, their Diabetes type 2 can be reversed and they may stop all their antidiabetic drugs.

It is as if two worlds exists in the treatment of type 2 diabetes.

One small world, based on the newest academic developments, see the light and the benefit of low-carbohydrate diets and intermittent fasting, for the reversal of diabetes type 2, while the older school, who believe in the Standard American Diet and the perception that diabetes type 2 is progressive and will eventually needs insulin.

The economic burden of T2D in the USA is $245 billion. One cannot stop wondering if the larger school that try to maintain the status qua is not under the influence of the big pharmaceutical budgets.

Lifestyle modifications are acknowledged to be the first-line treatment of T2D but is difficult to achieve in majority of obese patients. Bariatric surgery is an effective treatment option for obese patients with T2D, but is invasive, costly and not without its risks. Long-term effects have not been definitively established, and failure of the surgical intervention may occur due to non-compliance with diet and lifestyle factors. In addition, many patients require surgical reversal. Medications help manage the symptoms of diabetes, but they cannot prevent the progression of the disease.

Therapeutic fasting has the potential to fill this gap in diabetes care by providing similar intensive caloric restriction and hormonal benefits as bariatric surgery without the invasive surgery.

Therapeutic fasting is defined as the controlled and voluntary abstinence from all calorie-containing food and drinks from a specified period of time. During fasting periods, patients are allowed to drink unlimited amounts of very low-calorie fluids such as water, coffee and tea without sugar. On eating days, patients are encouraged to eat a diet low in sugar and refined carbohydrates, which decreases blood glucose and insulin secretion.

The case study of three patients on this regime with intermittent fasting had the following conclusions;

• All three patients stop using insulin.
• All three patients experienced drastic weight loss.
• All three patients had drastic fall in Hb1Ac levels.
• Therapeutic fasting is an underutilized intervention
that can provide superior blood glucose reduction. Fasting is a practical dietary strategy.
• With proper education and support, compliance is good.

Educating patients on the benefits of fasting in the management of T2D may aid in the remission of the disease and curtail the use of pharmacological interventions. A systematic review suggested that patients with T2D who have a baseline HbA1C of greater than 8% may achieve better glycaemic control when given individual education rather than usual care. Additionally, patients should be educated about and encouraged to follow an appropriate treatment plan tailored to them. Adherence to a fasting diet should continue to be stressed throughout treatment, because these lifestyle measures and modifications can have a large impact on the degree of diabetic control that patients can achieve, as seen with this case series.

Intermittent fasting replacing insulin in type 2 Diabetes. – Obesity & Diabetes Management – NewCare Life

Intermittent fasting replacing insulin in type 2 Diabetes. – Obesity & Diabetes Management – NewCare Life: This case series documents three patients referred to the Intensive Dietary Management clinic in Toronto, Canada, for insulin-dependent type 2 diabetes.

10% of statin users do get Diabetes type 2, one wonders why one more Statin tablet

Evacetrapib is a drug under development by Eli Lilly that inhibits cholesterolestertransfer protein. In a phase 2 trial it was seen as a wonder drug with the following effects:

• Decrease LDL levels by 35%.
• Increase HDL levels by 130%.

In a randomised control study by A. Michael Lincoff et all, the ACCELERATE trial, 12,092 patients with high cardiovascular risks received either Evacetrapid or Placebo. In spite of the massive difference in LDL values and HDL values as describes above, the primary endpoint results did not differ in patients receiving Evacetrapid or placebo.  With endpoint the following was taken into consideration; Strokes,myocardial  infarctions, revascularization procedures as well as admissions for unstable angina.

After 26 months of the trial was terminated due to a lack of efficacy of the treatment.

My Conclusion:

No wonder a lot of very serious questions are being asked about the merits of the Trillion Dollar statin industry. More and more conflicting reports start to appear that Statins have very little influence on the outcomes of serious cardiovascular complications. The effects of Evacetrapid on LDL levels and HDL levels are far better that any standard Statin therapy results.

If one considers the terrible side effects of Statins and the fact that 10% of statin users do get Diabetes type 2, one wonders why one more Statin tablet is being prescribed.

Metabolic Syndrome – Obesity

Metabolic Syndrome – Obesity: Metabolic syndrome is closely associated with obesity and knowledgeable scientists think it may approach 50-60% in South Africa and America.

Ketones form in the body when for some or other reason glucose

Suddenly observant people in the world are becoming aware of the term ketosis and what it can do about performance for athletes, benefit for diabetes and epilepsy, as well as treatment for cancer and Alzheimer’s disease.

I will tackle all the abovementioned topics in subsequent blogs, but want to dedicate this blog to the detail of ketosis.

Ketones form in the body when for some or other reason glucose can not be used for energy and fatty acids are being used for fuel instead of glucose.

The breakdown of fatty acids give rise to three keton bodies of which B-hydroxybuturic acid is the most important.

What are the common conditions where glucose is not available for fuel.

1) Type 1 Diabetes: body has no insulin and glucose can not be used for energy. The body has no other choice than to use ketones. Unfortunately in Diabetes type 1 patients, who do not receive insulin,  the level of ketones can become so high that  the patient can go into a keto-acidosis, that can be very dangerous.

2) Fasting: In fasting when there is no glucose for fuel the body resort to Fatty acids and ketones for fuel. For this reason people stranded in a boat at sea can stay alive for 30 days without food. By the way; humans are unique in the sense that they can resort to Fatty acids and ketones for fuel if they have no glucose to use.

Why did humans develop this exceptional skill amongst all animals?

They adapt over the years the mechanisms of changing their utilization between glucose fuel and ketone fuel. When they were hungry and had to hunt, they swithced to ketones which is a far better fuel than glucose, and went into top gear with performance and tact to catch a wild animal for food.

Now why is it  that doctors are afraid of this fuel which can supercharge human beings? The answer is quite simple: Type 1 diabetes patients who do not get insulin go  into a ketosis coma and can die easily. Their ketone levels is then in the order of 17 mm/litre. The “supercharge functional ketosis” is much lower at a level of 0,4-1,6 mm/Litre and  is very far removed from the keto-acidosis of Type 1 diabetes patients without insulin therapy.

How long will it take to change the attitude of doctors towards functional ketosis? I think about 50 years. I tried to explain it in detail to a experienced pathologist the other day. Her comment; I do not want to become cachectic.

In the meantime a lot of clever people will start getting the benefit and change their lives forever. Read More About https://obesityndiabetesmanagement.co.za